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Answers about Antihistamine

Answers about Antihistamine

A cold can bring a variety of obnoxious symptoms that interfere with day to day lives. While there is no cure for the common cold, there are medications to help relieve the symptoms. The Cold FAid® kit is composed of many medicines to help lessen the duration and severity of symptoms. Antihistamines, commonly known as allergy relief, are an essential part of the Cold FAid® strategy for cold relief. 

Many resources show the benefits that antihistamines have on cold symptoms. The FDA lists antihistamines on their non-prescription drugs in order to relieve a runny nose and sneezing.  The study ‘Antihistamines for the common cold’ explored the effect of the drug to relieve symptoms. They studied adults and children with the common cold as well as the positive effects of antihistamines versus placebo pills. When comparing the benefits at the beginning, middle, and end of the cold, short-term effects were seen when the medications were taken on day one and two. Minimal benefit was found when taken in the middle or end of a cold. This study also found that the side effects such as sedation do not outweigh the benefits. 

Antihistamines work by stopping your body from releasing histamine, an inflammatory chemical. Histamine is most commonly known for causing allergic symptoms such as  a runny nose, watery eyes and sneezing. This occurs because the immune system misinterprets what can be a harmless substance such as food, dust, pollen as harmful. It then releases histamine upon contact with that allergen causing an allergic reaction. The blood vessels become leaky and weepy - causing the above noted symptoms. Antihistamines primarily stabilize the immune cells (mast cells, basophils, and eosinophils) that would otherwise release the histamine or invite inflammation.  

A study looked at how first- and second-generation antihistamines impact the common cold. When ingested, both types of antihistamines stop what are termed ‘histaminic’ receptors. However, only first-generation antihistamines pass through the blood-brain barrier and also affect the ‘muscarinic’ receptors. It is this neuropharmaceutical effect on the brain (theorized to be primarily in the medulla) that limits the symptoms of sneezing, rhinorrhea, nasal mucus, and occasionally coughs. Therefore, only first-generation antihistamines are effective. 

In addition, when treating a cold, first-generation antihistamines’ optimal therapeutic benefit is reached when they are used in conjunction with decongestants. Studies have shown that antihistamines work concomitantly with decongestants to provide significant short-term benefits for cold symptoms. 

In order to get back to ‘normal life’ sooner,  use your Cold FAid® kit. Let that antihistamine aid in reducing symptoms! Become healthier faster. 



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